In such scenarios, the first thing that comes to mind is to reboot the computer, but if that does not help, you can refer to our blog and learn about the best solutions to fix Cursor Disappears in Windows 10. Your mouse pointer disappears usually when you wake up your system from sleep mode. The cursor disappears error has been noticed by users who have recently upgraded their system to Windows 10. Navigation through your Windows screen is quite simple with a mouse, however often there are situations where your mouse pointer might disappear.